NanoLinen Workshop
Physico-chemical aspects, toxicity and in-vitro methods

A symposium of the European Nanolinen Project

14-15 December 2011, Paris
Auditorium de la Grande Galerie de l’Évolution - Muséum National d'Histoire Naturelle



December, 14th

10h15 Nathalie Herlin - Marie Carriere Opening session: welcome
10h20- 10h30  Alok Dhawan (India) - Bensu Karahalil (Turkey) Introduction, the Nanolinen project
10h30- 11h10  Olivier Witschger, (INRS, France): Introduction conference Occupational exposure to airborne nanoparticles: Instrumentation, strategies and case studies
  Session 1: Nanoparticles, physico-chemical aspects  
11h10 – 11h50   Corinne Chaneac (College de France, France) Surface energy of oxide nanoparticles
11h50 – 12h20 Jean-Marie Hermann (IRCELYON, France) Impact of TiO2 nanoparticles on microorganisms in the dark or under UV light
12h 20 – 13h00 Keld Alstrup Jensen (Denmark) Assessment of hydrochemical reactivity and dosimetry of manufactured nanoparticles in different bioassays
  13h00-14h30 Lunch  
14h30-14h50 Eric Ansoborlo (CEA Marcoule) The toxicology program at CEA: a multidisciplinary approach of nanoparticules biological impacts
   Session 2: In vitro toxicity (CNT, TiO2)  
14h50-15h20 Sophie Lanone (INSERM, Créteil, France) Respiratory toxicity of nanoparticles
15h20-15h50 Dietmar Fuchs (Austria) TiO2 nanoparticles on human peripheral blood mononuclear cells
  15h50-16h20      Coffee break  
16h20 – 16h40 Jacques Aurelien Sergent (CEA, Fontenay aux Roses, France) TiO2 nanoparticle effects on human cell lines assessment, a present challenge: from characterization to new toxicological assessment
16h40 – 17h00 Vanessa Valdiglesias (Spain and Portugal) Toxicological effects of metal nanoparticles on human neuroblastoma cells

December, 15th

  Session 3: Alternative methods for evaluation of impact: proteomic, genomic, DNA repair  
9h30 – 10h20 Thierry Rabilloud (CNRS, Grenoble, France) Proteomic studies of the cellular responses to nanoparticles
10h20 – 11h00 Caroline Tokarski (CNRS, Lille, France) High resolution mass spectrometry for the study of protein expressions and modifications from cells exposed to nanoparticles
  11h00-11h30      Coffee break  
11h30- 12h20 Claude Emond (TINT, University of Montreal, Canada) Pharmacokinetic modelling for nanoparticles: What is it about?
12h20-13h00 Sylvie Sauvaigo (CEA, Grenoble, France) DNA repair microsystems
  13h00-14h30 Lunch  
  Session 4: Alternative methods to in vivo experiments. Development of in vivo / ex vivo models  
14h30-15h05 Hanns Rudolf Paur (KIT, Germany) Air-Liquid interface Exposure Systems for In-vitro studies of nanoparticle toxicity
15h05-15h40 Jeremy Pourchez (Ecole des mines, Saint Etienne, France) Deposition pattern of inhaled particles in the respiratory tract
15h40 – 16h00 Stefano Bonassi (Italy) Epidemiological issues with studies in human populations exposed to nanoparticles
16h00 – 16h20   Sandra Vranic (Universite Paris Diderot) Internalization of SiO2 nanoparticles by lung epithelial cells
16h20 – 16h40   Sabrina Barillet (University Paris-sud, Chatenay-Malabry, France) Immunotoxicity of nanoparticles, to be confirmed

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